Infertility and IVF applications

Applications of infertility and IVF:

Rooyagen "PRP" kit after success in several indications for use such as: musculoskeletal, chronic wounds, skin rejuvenation and hair loss treatment, each of which has a different platelet concentration and activity. with the latest results Research, the Rooyagen R&D team has successfully developed a clinical kit for infertility caused by RIF and thin endometrium has found clinical indications. Fortunately, it is used in most centers of the country.

The most important challenge facing PRP is the separation of enriched platelets in terms of concentration fold, efficiency, activity of platelet growth factors, type and number of lymphocytes for different uses. Confirmed by the clinical laboratory (at least for 1% of clients). Also, since 2016, the clinical use of PRP with code 302365 (with coefficient k20) has been mentioned in the tariff book of the Ministry of Health of the Islamic Republic of Iran.

Side effects:

There is no risk by following the instructions of Rooyagen Kit and contraindications. Due to the sensitivity of uterine tissue and the irreversibility of its side effects if not properly optimized and the use of inappropriate kits, it should be noted that knowing the specific requirements and sensitivities of IVF indication and infertility with other indications from Musculoskeletal sentences, beauty, chronic wounds, etc. are different and in some cases contradictory. With FERTILIZE LYMPHO PRP product based on evidence-based studies (EBM), Rooyagen has been able to offer different products approved by scientific journals and relevant experts.

Enrichment factor and intervals of use (injection):

For optimal PRP, platelet concentrations should be optimized, and for RIF and thin endometrium indications, this dose should be between 4 and 5 times the baseline value. The effectiveness of this range has been demonstrated in a trial using a Rooyagen kit. In the case of thin endometrium, it is twice at 48 hours, and in the case of RIF, once, 24 to 48 hours before embryo transfer.

Performance indicators and expected results:

The expected results in the mentioned infertility indicators have been shown in valid studies. Recently, lymphocyte-enriched platelets in the field of thin endometrium and RIF in IVF ward of Taleghani Hospital, Shahid Beheshti University of Medical Sciences It has been used with great success in the field of 100% curable thin endometrium. The success rate in RIF in the first phase of the study was about 80% and in the continuation of the study in women under 40 years of age, with a suitable endometrium and a fetus of good quality without genetic and immunological problems, about 66%.